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The Prevalence and Risk Factors for Neonatal Thrombocytopenia among Newborns Admitted to Intensive Care Unit of Aliasghar Children’s Hospital
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چکیده: (11123 مشاهده) |
| Background: Determining the prevalence and risk factors of thrombocytopenia among neonates enables us to
prevent the inevitable and sometimes irreversible complications. In this study we aimed to survey the frequency of
thrombocytopenia and its demographic features and risk factors.
Materials and methods: In this cross sectional study the platelet counts of 364 neonates admitted to neonatal
intensive care unit of Aliasghar children’s hospital, Tehran, Iran, were assessed. Maternal and neonatal medical
conditions, risk factors and drug history were also recorded. Patients were divided into 4 groups according to the
severity of thrombocytopenia: mild (100-149 × 109/L), moderate (50-99 × 109/L), severe (30-49 × 109/L) and very
severe (< 30 × 109/L).They were also grouped as presenting early (less than 72 hours after birth) and late (more than
72 hours after birth) thrombocytopenia. Demographic data and hemorrhagic manifestations were also recorded.
Results: Sixty two (17.9%) of neonates were thrombocytopenic. The average gestational age at birth for the
thrombocytopenic neonates was significantly lower than the non thrombocytopenic neonates (32.2 ±2.5 weeks
versus 34.9± 2.5, P=0.0001), and also the average birth weight was significantly lower among the thrombocytopenic
neonates (1979±517gr versus 2371±480 gr, P=0.0001). Neonatal sepsis was significantly associated with
thrombocytopenia (24.1% versus 5.9%, P=0.0001).
Conclusion: Our study indicated a high prevalence of thrombocytopenia among neonates admitted to NICU and its
association with low birth weight, prematurity, and neonatal sepsis. Regarding the importance of life threatening
events among the thrombocytopenic newborns, it is best to keep the risk factors in mind to prevent the future
complications.
Key words: Thrombocytopenia, risk factor, neonate, preterm |
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متن کامل [PDF 485 kb]
(3464 دریافت)
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: پژوهشي |
موضوع مقاله:
Pediatric Surgery
دریافت: 1391/4/27 | پذیرش: 1391/7/20 | انتشار: 1392/4/25
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