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:: Volume 6, Issue 3 (Spring 2014) ::
IJBC 2014, 6(3): 109-112 Back to browse issues page
In-Vitro Red Blood Cells Integrity and Morphology Changes after Passing Through Volumetric Peristaltic Infusion Pump
Hossein Esfahani * , Arash Dehghan , Hanieh Hosseini , Sara Esfahani
Abstract:   (14255 Views)
Background: It is not clear whether the use of volumetric peristaltic infusion pumps, affect the quality of the erythrocytes during packed cell transfusion or not. In the present study in vitro quality of red blood cells was assessed after using this type of infusion pumps in a prospective study. Materials and Methods: In this study 60 units of packed red cells were examined before and after passing through volumetric peristaltic infusion pumps. The shelf life of each bag was up to 7 days, and the transfusion rate was set to 40 milliliter/hour. Pre- and Post- infusion pump samples were analyzed for erythrocyte morphology and hemoglobin, potassium, lactate dehydrogenase and bilirubin levels. Samples obtained before the blood going through the infusion pumps were considered as the reference. Results: Infusion pump did not significantly increased the free hemoglobin, potassium, total bilirubin and lactate dehydrogenase increment, or fragmentation of the red blood cells, compared to the reference. Conclusion: Due to insignificant increase in free hemoglobin caused by erythrocyte destruction after passing through the volumetric peristaltic pumps in this in-vitro study, we suggest that these pumps can be safely used for transfusion of fresh packed cells. However clinical in-vivo studies on children and neonates are strongly recommended to ensure the safety and effectiveness of this new method of transfusion. Keywords: Infusion, blood, transfusion, hemolysis, erythrocytes.
Keywords: Infusion, blood, transfusion, hemolysis, erythrocytes
Full-Text [PDF 570 kb]   (1455 Downloads)    
: Research | Subject: Pediatric Hematology & Oncology
Received: 2013/05/11 | Accepted: 2014/01/24 | Published: 2014/04/8
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Esfahani H, Dehghan A, Hosseini H, Esfahani S. In-Vitro Red Blood Cells Integrity and Morphology Changes after Passing Through Volumetric Peristaltic Infusion Pump. IJBC. 2014; 6 (3) :109-112
URL: http://ijbc.ir/article-1-457-en.html


Volume 6, Issue 3 (Spring 2014) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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