[Home ] [Archive]    
:: Home :: About Journal :: Registration :: Article Submission :: Contact us :: Site Map ::
:: Volume 9, Issue 4 (December 2017 2017) ::
IJBC 2017, 9(4): 101-107 Back to browse issues page
Blood Pressure of Children and Adolescents with Sickle Cell Anemia in Basra, Iraq
Ammar Ali Hussain, Mea`ad Kadhum Hassan *
Department of Pediatrics, College of Medicine, University of Basra, Basra, Iraq
Abstract:   (1264 Views)
Background: Blood pressure in patients with sickle cell anemia (SCA) is influenced by autonomic cardiovascular dysfunction, endocrinopathies, nephropathy and nutritional factors. We aimed to evaluate systemic and diastolic blood pressure and its severity among children and adolescents with SCA and determine its association with clinical and hematological variables.
Methods: This case-control study included 112 patients with SCA (6-17 years old), registered at Basra Center for Hereditary Blood Diseases and 133 age and sex-matched healthy subjects as a control group. Complete examination was done for all subjects including anthropometric and BP measurements. Complete blood count, blood urea and serum creatinine were measured for all participants. A multivariate correlation analysis was used to assess contributing factors in BP.
Results: The systolic BP (SBP) and diastolic BP (DBP) curves of patients with SCA showed lower levels than control group for all age groups. Although both SBP and DBP readings were comparable at late adolescence. Pre-hypertension was reported in 5 (4.4%) patients and 3 (2.4%) healthy subjects. Multivariate analysis revealed that SBP and DBP among patients with SCA had significant positive association with age, weight, height, body mass index, hemoglobin and blood transfusion history and a negative association with heart rate ( P<0.05).
Conclusion: Our findings supported previous reports of lower BP in patients with SCA. Furthermore, routine BP measurements in pediatric patients with SCA is important for early detection of pre-hypertension to establish an effective treatment.
Keywords: Blood pressure, Sickle cell anemia, Children, Systolic blood pressure, Diastolic blood pressure, Anemia, Growth parameters
Full-Text [PDF 748 kb]   (584 Downloads)    
: Research | Subject: Pediatric Hematology & Oncology
Received: 2017/08/25 | Accepted: 2017/12/25 | Published: 2018/03/4
* Corresponding Author Address: Department of Pediatrics, College of Medicine, University of Basra
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hussain A A, Hassan M K. Blood Pressure of Children and Adolescents with Sickle Cell Anemia in Basra, Iraq. IJBC. 2017; 9 (4) :101-107
URL: http://ijbc.ir/article-1-756-en.html

Volume 9, Issue 4 (December 2017 2017) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
Persian site map - English site map - Created in 0.06 seconds with 31 queries by YEKTAWEB 3877