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:: Volume 8, Issue 4 (December 2016) ::
IJBC 2016, 8(4): 98-102 Back to browse issues page
Clinicopathological Features of Patients with Non-small-cell Lung Cancer in West of Iran
Mehrdad Payandeh , Masoud Sadeghi * , Edris Sadeghi
MSc Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Abstract:   (969 Views)

Background: Lung cancer is the most common cause of cancer death worldwide with an annual mortality rate of more than 1.3 million worldwide. We aimed to analyze the clinicopathological features of patients with non-small-cell lung cancer (NSCLC) in west of Iran.
Methods: 64 patients with NSCLC who referred to our clinic were analyzed. Sex, age, histopathology, location of the tumor, treatment, sites of metastasis and overall survival of the patients were studied. EGFR mutations were analyzed using th DxS kit with Multiplex allele specific real-time PCR×29 primers (ARMS Method), DxS Scorpion and ARMS assay.
Results: Mean age of the patients at diagnosis was 60 years. 51 (79.7%) patients were men. 34.3% were in their sixth to seventh decade of life (50-69 years). 40 (68.75%) patients had distant metastasis to bone and liver as the most common sites. Adenocarcinoma, squamous cell carcinoma and large cell carcinoma were observed in 68.8%, 23.3%, and 7.9% of the patients, respectively. 3-year survival rate was 25% and the mean overall survival (OS) was 16 months for all patients. Conclusion: The mean age of Iranian patients with lung cancer in a western province of Iran was between 55-65 years in our study. Metastasis to bone was more common than other studies. Also, the OS in this study was higher than the other studies.

Full-Text [PDF 530 kb]   (484 Downloads)    
: Research | Subject: Adults Hematology & Oncology
Received: 2016/08/1 | Accepted: 2016/11/17 | Published: 2017/01/4
* Corresponding Author Address: Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
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Payandeh M, Sadeghi M, Sadeghi E. Clinicopathological Features of Patients with Non-small-cell Lung Cancer in West of Iran. IJBC. 2016; 8 (4) :98-102
URL: http://ijbc.ir/article-1-679-en.html


Volume 8, Issue 4 (December 2016) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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