Volume 11, Issue 4 ( December 2019 2019)                   Iranian Journal of Blood and Cancer 2019, 11(4): 139-142 | Back to browse issues page

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Pneumothorax and Acute Kidney Injury in the Early Phase of Acute Lymphoblastic Leukemia Induction Therapy due to Aspergillus Fumigatus and Pneumocystis Jirovecii Co-Infection: A Case Report
Parinaz Sedighi1 , Hossein Esfahani *2
1- Student research committee, Hamadan University of Medical Sciences
2- Hamadan University of Medical Sciences , hesfehani@yahoo.com
Abstract:   (4217 Views)
Leukemia is the most common malignancy in children which leads to immunosuppression and predisposes patients to opportunistic infections. We report a 12-year-old girl with acute lymphoblastic leukemia (ALL) who developed simultaneous infection with pneumocystis Jirovecii pneumonia and aspergillosis in the induction phase of chemotherapy. The patient developed pulmonary cavitation and pneumothorax which was treated with trimethoprim-sulfamethoxasole in addition to intravenous liposomal Amphotrecin B. Pediatric oncologists should consider concurrent co-infection of opportunistic infections such as aspergillus fumigatus and Pneumocystis Jirovecii in immunocompromised patients especially if pneumothorax develops in early stages of disease or immunosuppressive therapy.
Keywords: Acute Lymphoblastic Leukemia, Aspergillus Fumigatus, Pneumocystis Jirovecii Pneumonia, Pneumothorax, Cavitation
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: Case report | Subject: Pediatric Hematology & Oncology
Received: 2019/04/25 | Accepted: 2019/12/13 | Published: 2020/01/27
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