%0 Journal Article %A Chetak, K.B %A Hiremath, Vilas %A Sujay, K R %A Dinesh Kumar, U S %A Jagadish kumar, K %T Congenital Hypofibrinogenemia Detected during Preoperative Workup for Major Cardiac Surgery %J Iranian Journal of Blood and Cancer %V 10 %N 3 %U http://ijbc.ir/article-1-808-en.html %R %D 2018 %K Congenital hypofibrinogenemia, Afibrinogenemia, Cardiac surgery, Coagulation screening tests, Prolonged prothrombin time, Thrombin time, %X Afibrinogenemia or hypofibrinogenemia is a quantitative defect in fibrinogen. It is a rare disease with estimated frequency of 1 in 1,000,000 population. Routine preoperative screening tests of coagulation disorders are insufficient to detect subtle disorders of fibrinogen. Herein, we report a child who was supposed to undergo open cardiac surgery for a large atrial septal defect. Preoperative coagulation screening tests revealed minimal prolongation of prothrombin time which made us do further work-up. Finally, she was diagnosed with hypofibrinogenemia who was suggested to be congenital. %> http://ijbc.ir/article-1-808-en.pdf %P 96-98 %& 96 %! %9 Case report %L A-10-375-1 %+ %G eng %@ 2008-4595 %[ 2018