RT - Journal Article T1 - Acute Lymphoblastic Leukemia Switch Lineage upon Relapse to Acute Bilineage Leukemia: A Case Report JF - IJBC YR - 2021 JO - IJBC VO - 13 IS - 1 UR - http://ijbc.ir/article-1-1026-en.html SP - 22 EP - 25 K1 - Acute lymphoblastic leukemia (ALL) K1 - Lineage switch K1 - Mixed-phenotype acute leukemias (MPALs) K1 - Acute bilineage leukemia AB - Although acute leukemia commonly relapses in adults, the conversion of leukemic cell lineage (lymphoid or myeloid) upon relapse has rarely taken place. “Lineage switch” is a term widely used to define the leukemic lineage transformation as assessed by morphology, cytochemistry, and immunophenotyping from diagnosis to relapse. In most lineage switch cases, B-cell lymphoblastic leukemia/lymphoma relapses as acute myeloid leukemia or vice versa. Here, we report an exceedingly rare case of T-cell acute lymphoblastic leukemia relapsing as mixed-phenotype acute leukemia. LA eng UL http://ijbc.ir/article-1-1026-en.html M3 ER -