TY - JOUR JF - IJBC JO - Iranian Journal of Blood and Cancer VL - 11 IS - 4 PY - 2019 Y1 - 2019/12/01 TI - Pneumothorax and Acute Kidney Injury in the Early Phase of Acute Lymphoblastic Leukemia Induction Therapy due to Aspergillus Fumigatus and Pneumocystis Jirovecii Co-Infection: A Case Report TT - N2 - Leukemia is the most common malignancy in children which leads to immunosuppression and predisposes patients to opportunistic infections. We report a 12-year-old girl with acute lymphoblastic leukemia (ALL) who developed simultaneous infection with pneumocystis Jirovecii pneumonia and aspergillosis in the induction phase of chemotherapy. The patient developed pulmonary cavitation and pneumothorax which was treated with trimethoprim-sulfamethoxasole in addition to intravenous liposomal Amphotrecin B. Pediatric oncologists should consider concurrent co-infection of opportunistic infections such as aspergillus fumigatus and Pneumocystis Jirovecii in immunocompromised patients especially if pneumothorax develops in early stages of disease or immunosuppressive therapy. SP - 139 EP - 142 AU - Sedighi, Parinaz AU - Esfahani, Hossein AD - Hamadan University of Medical Sciences KW - Acute Lymphoblastic Leukemia KW - Aspergillus Fumigatus KW - Pneumocystis Jirovecii Pneumonia KW - Pneumothorax KW - Cavitation UR - http://ijbc.ir/article-1-891-en.html ER -