en Pediatric Hematology & Oncology Pediatric Hematology & Oncology پژوهشي Original Article Background: In the past 20 years, a dramatic improvement in the prognosis of patients with hepatoblastoma (HB)<br>has been achieved by combining surgery and chemotherapy in several national and international trials.<br>Materials and Methods: Four children ( 3 girl and 1 boy) aged 34 days, 4 months, 13 months, and 1 year with mean<br>age of 6.53 (±5.15) months were presented to our center from 2002 to 2009 with abdominal mass and abdominal<br>distention. Their abdominal ultrasonography revealed liver mass, and pathological diagnosis was hepatoblasma.<br>They were treated with a combination of surgery and chemotherapy.<br>Results: Patients with non-metastatic HB were treated at Shahid Sadoughi Hospital of Yazd. A complete resection of<br>primary tumor was achieved in all of them. The median follow- up of the patients was 38.25 (± 29.02) month and all<br>of them (100%) remained alive with complete remission.<br>Conclusion: Complete resection with chemotherapy can improve prognosis of hepatoblastoma patients. Hepatoblastoma, Chemotherapy, Cisplatin, doxorubicin 87 90 http://ijbc.ir/browse.php?a_code=A-10-2-176&slc_lang=en&sid=1