en Adults Hematology & Oncology Adults Hematology & Oncology پژوهشي Original Article <p>Background: Triple negative breast cancer (TNBC) is reported to be associated with a high risk of recurrence, poor overall survival (OS), and disease-free survival (DFS) rates. This study evaluated the clincopathological features and survival of non-metastatic TNBC women in the capital of Iran compared with other areas of the world.<br> Methods: In a retrospective study, 119 women with TNBC based on the criteria were analyzed in this study during 2007-2015. A number of clinicopathological variables, OS and DFS were determined in all patients. The mean follow-up was 38 months, which 6 patients lost to follow-up and 16 died of the disease and therefore were censored from the study.&nbsp;<br> Results: The mean age at diagnosis was 44.9 years (range: 21-85 years). 31.9% were older than 50 years. The 2- and 5-years OS rates were 96% and 88.1%, respectively; whereas, the 2- and 5-years DFS rates were 87% and 74.1%, respectively. Right breast tumor and lymph node involvement were more common in patients younger than 50 years, but vascular invasion was more observed in patients aged &ge;50 years. There was no significant difference between menopause status, age and Ki-67 index for OS or DFS.&nbsp;<br> Conclusion: The prevalence of TNBC was more common in women younger than 50 years. Ki-67 index, menopausal status and age could contribute to prognosis and survival of patients.</p> Breast cancer, Overall survival, Disease free survival, Prognostic factors, Triple negative, Estrogen receptor, Progesterone receptor, HER2 receptors 18 23 http://ijbc.ir/browse.php?a_code=A-10-218-13&slc_lang=en&sid=1 Safa Najafi safa3n@yahoo.com 10031947532846003577 10031947532846003577 No Breast Cancer Research Centre, ACECR, Tehran, Iran Hamid Reza Mozaffari mozaffari20@yahoo.com 10031947532846003578 10031947532846003578 No Department of Oral Medicine, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran; Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran Masoud Sadeghi sadeghi_mbrc@yahoo.com 10031947532846003579 10031947532846003579 Yes Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran; Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran