en Pediatric Hematology & Oncology Pediatric Hematology & Oncology گزارش مورد Case report <span dir="LTR"></span> Leukemia is the most common malignancy in children which leads to immunosuppression and predisposes patients to opportunistic infections. We report a 12-year-old girl with acute lymphoblastic leukemia (ALL) who developed simultaneous infection with pneumocystis Jirovecii pneumonia and aspergillosis in the induction phase of chemotherapy. The patient developed pulmonary cavitation and pneumothorax which was treated with trimethoprim-sulfamethoxasole in addition to intravenous liposomal Amphotrecin B. Pediatric oncologists should consider concurrent co-infection of opportunistic infections such as aspergillus fumigatus and Pneumocystis Jirovecii in immunocompromised patients especially if pneumothorax develops in early stages of disease or immunosuppressive therapy. Acute Lymphoblastic Leukemia, Aspergillus Fumigatus, Pneumocystis Jirovecii Pneumonia, Pneumothorax, Cavitation 139 142 http://ijbc.ir/browse.php?a_code=A-10-60-3&slc_lang=en&sid=1 Parinaz Sedighi psedighi95@gmail.com 10031947532846005090 10031947532846005090 No Student research committee, Hamadan University of Medical Sciences Hossein Esfahani hesfehani@yahoo.com 10031947532846005091 10031947532846005091 Yes Hamadan University of Medical Sciences