Volume 13, Issue 1 ( March 2021 2021)
Iranian Journal of Blood and Cancer 2021, 13(1): 22-25 |
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1- Hematology Division of Internal Medicine Department, Isfahan University of Medical Sciences, Isfahan, Iran
2- Pathology Department, OMID Professional Hospital, Isfahan University of Medical Science
2- Pathology Department, OMID Professional Hospital, Isfahan University of Medical Science
Abstract: (2478 Views)
Although acute leukemia commonly relapses in adults, the conversion of leukemic cell lineage (lymphoid or myeloid) upon relapse has rarely taken place. “Lineage switch” is a term widely used to define the leukemic lineage transformation as assessed by morphology, cytochemistry, and immunophenotyping from diagnosis to relapse. In most lineage switch cases, B-cell lymphoblastic leukemia/lymphoma relapses as acute myeloid leukemia or vice versa. Here, we report an exceedingly rare case of T-cell acute lymphoblastic leukemia relapsing as mixed-phenotype acute leukemia.
Keywords: Acute lymphoblastic leukemia (ALL), Lineage switch, Mixed-phenotype acute leukemias (MPALs), Acute bilineage leukemia
: Case report |
Subject:
Adults Hematology & Oncology
Received: 2020/06/20 | Accepted: 2021/04/6 | Published: 2021/05/23
Received: 2020/06/20 | Accepted: 2021/04/6 | Published: 2021/05/23
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