, Asghar Dasmeh2 , Amir Yousef Farahmandi3 , Azam Khedri4 , Fatemeh Asadi5 , Fahimeh Piryaei * 6, Leila Moradi7
2- Unit of Health, Mahshahr petrochemical industries hospital, Bandar Mahshahr, Khuzestan, Iran
3- Department of English, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
4- Department of Clinical Biochemistry, Faculty of Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
5- Department of Molecular Genetics, Science and Research Branch, Islamic Azad University, Fars, Iran
6- Department of Molecular Medicine and Genetics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
7- Department of Epidemiology, School of Public Health, Hamadan University of Medical, Hamadan, Iran
Coronavirus Disease 2019 (COVID-19) is a significant medical and public health problem in the world. It is believed that it can worsen in extreme conditions. Also, it is suggested that blood disorders such as sickle cell disease (SCD) may increase the risk of COVID-19 symptoms. The present study reports a family facing COVID-19, in which one of two members with SCD presented with fever, repeated cough and dizziness followed by acute chest syndrome leading to death. The remained members that had sickle cell trait manifested mild symptoms based on our findings. Although COVID-19 in individuals with SCD showed an increased risk for COVID19 compared with individuals with sickle cell trait, it seems that SCD cannot lead to worse condition in our patients.
Received: 2020/11/11 | Accepted: 2021/07/3 | Published: 2021/07/15
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