Iranian Journal of Blood and Cancer
Iranian Journal of Blood and Cancer
Medical Sciences
http://ijbc.ir
1
admin
2008-4595
2008-4609
8
10.61186/ijbc
14
2008-4595
13
en
jalali
1393
8
1
gregorian
2014
11
1
7
1
online
1
fulltext
en
A Review of Procedures Involved in Human Umbilical Cord Blood Banking and Transplantation
Pediatric Hematology & Oncology
Pediatric Hematology & Oncology
مقاله مروری
Review Article
Cord blood hematopoietic stem cells are widely used as an alternative source for hematopoietic stem cells transplant. Increasing rate of patients who need hematopoietic stem cells transplant and many advantages of cord blood in comparison to bone marrow hematopoietic stem cells, have promoted banking of cord blood units. Cord blood banking requires accurate steps in donor selection, cord blood collection, processing, cryopreservation and finally screening and testing of the units. The main limitation of umbilical cord blood transplantation is cell dose and resolving this limitation is vital in avoiding frequent problems in hematopoietic stem cells transplant. Transplantation of more than one unit and ex vivo expansion of umbilical cord blood units, decrease these limitation. Furthermore, the international standard guidelines have been published by the Foundation for the Accreditation of Cellular Therapy (FACT)-NetCord to improve the quality of units and simulation of cord blood banks activities. This review presents a general overview on cord blood banking and related activities and its improvement during last two decades.
Keywords: Blood banking, cord blood, hematopoietic stem cells.
Blood banking, cord blood, hematopoietic stem cells.
37
42
http://ijbc.ir/browse.php?a_code=A-10-9-19&slc_lang=en&sid=1
Nikougoftar Zarif
M
10031947532846002700
10031947532846002700
Yes