en Pathology Pathology گزارش مورد Case report Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease with diverse clinical manifestations involving multiple organ systems. Peritoneal involvement as a sign of gastrointestinal disease in SLE is a rare condition. Massive ascites as the initial manifestation of SLE is an extremely rare situation. Here, we report a 13-year-old female with bile-stained vomiting, ascites and signs of pseudo-obstructions with a past medical history of immune thrombocytopenic purpura (ITP) who was later diagnosed to have SLE. Systemic lupus erythematous, Ascites, Pseudo-obstruction, Lymphadenopathy, Protein-losing enteropathy, Peritoneal involvement, Immune thrombocytopenic, Purpura 67 69 http://ijbc.ir/browse.php?a_code=A-10-522-1&slc_lang=en&sid=1 Reza Jafari rezajafari201089@gmail.com 10031947532846005643 10031947532846005643 No Department of Radiology, Baqiyatallah University of Medical Sciences, Tehran, Iran and Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran Hassan Abolghasemi abolghasemi@ibto.ir 10031947532846005644 10031947532846005644 No Department of Pediatrics, Baqiyatallah University of Medical Sciences, Tehran, Iran Mohammad Javanbakht محمد جوانبخت armanjvbt81@gmail.com 10031947532846005645 10031947532846005645 No Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran Zahra Najjari zahranajjarii@yahoo.com 10031947532846005646 10031947532846005646 No Department of Pediatrics, Baqiyatallah University of Medical Sciences, Tehran, Iran Fatemeh Beiraghdar f.beiraghdar@ijnu.ir 10031947532846005647 10031947532846005647 No Department of Pediatrics, Baqiyatallah University of Medical Sciences, Tehran, Iran Zohreh Kavehmanesh mhmjvbt81@gmail.com 10031947532846005648 10031947532846005648 Yes Department of Pediatrics, Baqiyatallah University of Medical Sciences, Tehran, Iran