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:: Volume 11, Issue 2 (June 2019 2019) ::
IJBC 2019, 11(2): 47-50 Back to browse issues page
Evaluating the Frequency of Human T-Lymphotropic Virus Type 1 Infection in Iranian Population
Shirin Ferdowsi, Mahsa Najafzadeh, Mohammad Reza Ameli, Seyed Mehdi Sajjadi *
Cellular and molecular research center, Birjand university o medical sciences
Abstract:   (863 Views)

Background: Human T-cell lymphotropic viruses 1 (HTLV1) is endemic in specific regions. We aimed to determine the prevalence of HTLV I infection among blood donors in southeast Iran.  
Methods: This cross-sectional study was conducted between April 2005 and March 2015. Sera were collected from blood donors and were tested for the presence of HTLV1 specific antibody using ELISA. Reactive samples were then tested by Western blot for confirmation.
Results: Of the 165,267 blood donors tested for HTLV 1 antibody, 45 (0.027%) donors were positive. Out of 45 positive donors, 41 were first time blood donors, 3 were repeat blood donors and 1 as regular donor. Most HTLV-1-positive donors were male and married. Co-infection with HBV was observed in one subject. The percentage of positive samples had increasing patterns from 0.016% in 2009 to 0.084% in 2010 and decreased after that to 0.014% in 2015.
Conclusion: The results indicated a low level of infection of HTLV1 in this part of our country. 

Keywords: HTLV infection, Blood donors, Prevalence, Seropositivity
Full-Text [PDF 443 kb]   (238 Downloads)    
: Research | Subject: Infectious Diseases
Received: 2018/12/22 | Accepted: 2019/08/17 | Published: 2019/08/17
* Corresponding Author Address: Birjand, Iran
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Ferdowsi S, Najafzadeh M, Ameli M R, Sajjadi S M. Evaluating the Frequency of Human T-Lymphotropic Virus Type 1 Infection in Iranian Population. IJBC. 2019; 11 (2) :47-50
URL: http://ijbc.ir/article-1-866-en.html

Volume 11, Issue 2 (June 2019 2019) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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