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Serum Antioxidant Levels in Children with Beta-Thalassemia Major
چکیده:   (6483 مشاهده)
Background: Thalassemia represents a serious health problem in Iran because of its heterogeneous frequency and the existing endogamy system. It is an inherited blood disease characterized by the under production of normal hemoglobin, the oxygen-carrying protein in red blood cells. Materials and Methods: In this study, serum antioxidants including selenium (Se), zinc (Zn) and copper (Cu) were measured using atomic absorption spectrometry (AAS) in children with beta-thalassemia major (n=40) and compared with the control group (n=40). Results: There were significant differences in the values of Se, Zn and Cu between the two groups. Se and Zn levels were 41.78±22.87 μg/l and 61.70±13.25 μg/dl in thalassemia, but 108.63±25.79 μg/l and 114.72±23.70 μg/dl in healthy children. Meanwhile, Cu levels were 156.60±22.62 and 102.88±31.15 μg/dl among patients and controls, respectively. Conclusion: This study shows that Se, Zn and Cu may play a role in the pathogenesis of beta-thalassemia major. Key words: Beta-thalassemia, antioxidants, children
متن کامل [PDF 436 kb]   (1683 دریافت)    
: گزارش مورد | موضوع مقاله: Pediatric Hematology & Oncology
دریافت: ۱۳۹۱/۱۱/۲۵ | پذیرش: ۱۳۹۳/۱۰/۱۳ | انتشار: ۱۳۹۳/۱۰/۱۳
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Farzin L, Sajadi F, Kupai L. Serum Antioxidant Levels in Children with Beta-Thalassemia Major . IJBC. 2011; 4 (1) :1-5
URL: http://ijbc.ir/article-1-369-fa.html

Serum Antioxidant Levels in Children with Beta-Thalassemia Major . مجله خون و سرطان ايران. 1390; 4 (1) :1-5

URL: http://ijbc.ir/article-1-369-fa.html



دوره 4، شماره 1 - ( 9-1390 ) برگشت به فهرست نسخه ها
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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