Volume 14, Issue 3 ( September 2022 2022)                   Iranian Journal of Blood and Cancer 2022, 14(3): 32-40 | Back to browse issues page


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Tamaddon G, Fazeli P, saeidnia M, Farzi A, Pooresmaeil N, Javanmardi M H. Evans syndrome in the course of COVID-19 infection; Essentials and approaches. Iranian Journal of Blood and Cancer 2022; 14 (3) :32-40
URL: http://ijbc.ir/article-1-1216-en.html
1- Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. tamaddon.g@gmail.com , tamaddon.g@gmail.com
2- Shiraz Medical Sciences
3- Ilam Medical Sciences
Abstract:   (919 Views)

Redundant studies proved coronavirus infection results from a defect in a suitable immune response that may exacerbate immune-inflammatory reactions like cytokine storm and autoimmunity. Evans syndrome (ES) is a rare chronic autoimmune disease that distinguishes it from autoimmune hemolytic anemia (AIHA) and immune thrombocytopenic purpura (ITP). Reports have shown significant differences in immune cells and laboratory parameters in Evans syndrome/COVID-19 co-infected patients. Also, the contribution between autoimmune diseases and SARS-CoV-2 infection could result in immune response disequilibrium that considers a possible mechanism for ES development. Moreover, we will briefly explain the double-edged sword role of immunosuppressive drugs in Evans syndrome/COVID-19 co-infected patients. Generally, the pathophysiology of SARS-CoV-2 in hematologic autoimmune disorders progression, particularly ES, remains unclear, but some investigations explain the COVID-19 infection mechanism in the mentioned disorders development. The purpose of the current study is to look at the coronavirus effects on Evans syndrome aggravation, the immune cells and laboratory markers alterations in Evans syndrome/COVID-19 co-infected patients, the coronavirus effects on Evans syndrome patients during their pregnancy, and the Evans syndrome / COVID-19 co-infected patient management.

Full-Text [PDF 520 kb]   (613 Downloads)    
: Review Article | Subject: Immunology
Received: 2022/01/12 | Accepted: 2022/08/16 | Published: 2022/09/19

References
1. Taherifard E, Taherifard E, Movahed H, Mousavi MRJH. Hematologic autoimmune disorders in the course of COVID-19: a systematic review of reported cases. 2021;26(1):225-39. [DOI:10.1080/16078454.2021.1881225]
2. Lippi G, Plebani M, Henry BMJCca. Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis. 2020;506:145-8. [DOI:10.1016/j.cca.2020.03.022]
3. Vadlamudi G, Hong L, Keerthy MJCRiO, Gynecology. Evans syndrome associated with pregnancy and COVID-19 infection. 2020;2020. [DOI:10.1155/2020/8862545]
4. Abbas AM, Helbawi FM, Abdelsalam MHJJoBR, Sciences E. Treatment of People with Evans Syndrome in the Setting of COVID-19 Pandemic. 2020;6(9):160-2. [DOI:10.37871/jbres1137]
5. Abbas AM, Helbawi FM, Abdelsalam MHJJI. Treatment of People with Evans Syndrome in the Setting of COVID-19 Pandemic. 2020;2766:2276. [DOI:10.37871/jbres1137]
6. Jaime-Pérez JC, Aguilar-Calderón PE, Salazar-Cavazos L, Gómez-Almaguer DJJobm. Evans syndrome: clinical perspectives, biological insights and treatment modalities. 2018;9:171. [DOI:10.2147/JBM.S176144]
7. Demir NA, Basturk A, Ural O, Sumer S, Erdogdu B, Kiratli HE, Celik JB, Koplay M, Vatansev HJBT. A case of Evans syndrome secondary to COVID-19. 2021;19(1):85.
8. Li M, Nguyen CB, Yeung Z, Sanchez K, Rosen D, Bushan SJBJoH. Evans syndrome in a patient with COVID‐19. 2020. [DOI:10.1111/bjh.16846]
9. Aladjidi N, Fernandes H, Leblanc T, Vareliette A, Rieux-Laucat F, Bertrand Y, Chambost H, Pasquet M, Mazingue F, Guitton CJFip. Evans syndrome in children: long-term outcome in a prospective French national observational cohort. 2015;3:79. [DOI:10.3389/fped.2015.00079]
10. Couri FS, Kandula MJTAjocr. A Case of Evans Syndrome with Acute Hemolysis and Hemoglobin Cast Nephropathy. 2020;21:e920760-1. [DOI:10.12659/AJCR.920760]
11. EVANS RS, Takahashi K, DUANE RT, Payne R, Liu C-KJAaoim. Primary thrombocytopenic purpura and acquired hemolytic anemia: evidence for a common etiology. 1951;87(1):48-65. [DOI:10.1001/archinte.1951.03810010058005]
12. Michel M, Chanet V, Dechartres A, Morin A-S, Piette J-C, Cirasino L, Emilia G, Zaja F, Ruggeri M, Andres EJB, The Journal of the American Society of Hematology. The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases. 2009;114(15):3167-72. [DOI:10.1182/blood-2009-04-215368]
13. Marieke Schoonen W, Kucera G, Coalson J, Li L, Rutstein M, Mowat F, Fryzek J, Kaye JAJBjoh. Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database. 2009;145(2):235-44. [DOI:10.1111/j.1365-2141.2009.07615.x]
14. Aladjidi N, Leverger G, Leblanc T, Picat MQ, Michel G, Bertrand Y, Bader-Meunier B, Robert A, Nelken B, Gandemer VJh. New insights into childhood autoimmune hemolytic anemia: a French national observational study of 265 children. 2011;96(5):655. [DOI:10.3324/haematol.2010.036053]
15. Teachey DT, Manno CS, Axsom KM, Andrews T, Choi JK, Greenbaum BH, McMann JM, Sullivan KE, Travis SF, Grupp SAJB. Unmasking Evans syndrome: T-cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS). 2005;105(6):2443-8. [DOI:10.1182/blood-2004-09-3542]
16. Savaşan S, Warrier I, Buck S, Kaplan J, Ravindranath YJCi. Increased lymphocyte Fas expression and high incidence of common variable immunodeficiency disorder in childhood Evans' syndrome. 2007;125(3):224-9. [DOI:10.1016/j.clim.2007.08.010]
17. Lochowicz AJ, Curtis BRJLM. Clinical applications of platelet antibody and antigen testing. 2011;42(11):687-92. [DOI:10.1309/LMM242GKGHCKJRWI]
18. Jasinski S, Weinblatt ME, Glasser CLJJopho. Sirolimus as an effective agent in the treatment of Immune Thrombocytopenia (ITP) and Evans Syndrome (ES): a single institution's experience. 2017;39(6):420-4. [DOI:10.1097/MPH.0000000000000818]
19. Malić Tudor K, Čulić S, Armanda V, Kuljiš DJPC. Successful treatment with rituximab in boy with Evans syndrome-case report. 2017;61(4):187-90.
20. Sulpizio ED, Raghunathan V, Shatzel JJ, Zilberman‐Rudenko J, Worrest T, Sheppard BC, DeLoughery TGJEjoh. Long‐term remission rates after splenectomy in adults with Evans syndrome compared to immune thrombocytopenia: A single‐center retrospective study. 2020;104(1):55-8. [DOI:10.1111/ejh.13336]
21. Teachey DT, Lambert MP. Diagnosis and management of autoimmune cytopenias in childhood. Pediatric clinics of North America. 2013;60(6):1489-511. [DOI:10.1016/j.pcl.2013.08.009]

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