Kaposiform Hemangioendothelioma of Abdominal Wall Associated with Kasabach-Merritt in A Newborn with Dramatic Response to Sirolimus and Vincristine

Alavi, Samin

doi:10.58209/ijbc.14.1.46

Volume 14, Issue 1 ( March 2022 2022) Iranian Journal of Blood and Cancer 2022, 14(1): 46-48 | Back to browse issues page

‎ 10.58209/ijbc.14.1.46

Mendeley

Zotero

RefWorks

Alavi S. Kaposiform Hemangioendothelioma of Abdominal Wall Associated with Kasabach-Merritt in A Newborn with Dramatic Response to Sirolimus and Vincristine. Iranian Journal of Blood and Cancer 2022; 14 (1) :46-48
URL: http://ijbc.ir/article-1-1249-en.html

Kaposiform Hemangioendothelioma of Abdominal Wall Associated with Kasabach-Merritt in A Newborn with Dramatic Response to Sirolimus and Vincristine

Samin Alavi ^*

Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children’s health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract: (1401 Views)

Kaposiform Hemangioendotheliomawas (KHE) first described in 1993 by Zukerberg and colleagues as a distinctive lesion of infancy and early childhood with common features to both hemangiomas and Kaposi’s sarcoma. It is a rare vascular tumor typically seen as a cutaneous lesion with ill-defined borders. In this study we presented A 26-day-old male infant with KHE.

Keywords: Kaposiform Hemangioendothelioma, Kasabach-Merritt, Vincristine, Sirolimus.

Full-Text [PDF 1075 kb] (493 Downloads)

: Special Issue | Subject: Adults Hematology & Oncology
Received: 2022/04/30 | Accepted: 2022/03/10 | Published: 2022/04/30

References

1. Zukerberg, L.R., B.J. Nickoloff, and S.W. Weiss, Kaposiform hemangioendothelioma of infancy and childhood. An aggressive neoplasm associated with Kasabach-Merritt syndrome and lymphangiomatosis. The American journal of surgical pathology, 1993. 17(4): p. 321-328. [DOI:10.1097/00000478-199304000-00001]

2. Fletcher, C., et al., WHO Classification of Tumours of Soft Tissue and Bone: WHO Classification of Tumours, vol. 5. 2013.

3. Croteau, S.E., et al., Kaposiform hemangioendothelioma: atypical features and risks of Kasabach-Merritt phenomenon in 107 referrals. The Journal of pediatrics, 2013. 162(1): p. 142-147. [DOI:10.1016/j.jpeds.2012.06.044]

4. Sarkar, M., et al., Thrombocytopenic coagulopathy (Kasabach-Merritt phenomenon) is associated with Kaposiform hemangioendothelioma and not with common infantile hemangioma. Plastic and reconstructive surgery, 1997. 100(6): p. 1377-1386. [DOI:10.1097/00006534-199711000-00001]

5. Ji, Y., et al., Kaposiform haemangioendothelioma: clinical features, complications and risk factors for Kasabach-Merritt phenomenon. British Journal of Dermatology, 2018. 179(2): p. 457-463. [DOI:10.1111/bjd.16601]

6. Adams, D.M., et al., Vascular anomaly cases for the pediatric hematologist oncologists-an interdisciplinary review. Pediatric Blood & Cancer, 2018. 65(1): p. e26716. [DOI:10.1002/pbc.26716]

7. Mahajan, P., J. Margolin, and I. Iacobas, KasabachMerritt phenomenon: classic presentation and management options. Clinical Medicine Insights: Blood Disorders, 2017. 10: p. 1179545X17699849. [DOI:10.1177/1179545X17699849]

8. Rodriguez, V., et al., Kasabach-Merritt phenomenon: case series and retrospective review of the mayo clinic experience. Journal of pediatric hematology/ oncology, 2009. 31(7): p. 522-526. [DOI:10.1097/MPH.0b013e3181a71830]

9. Liu, Q., et al., Clinicopathological features of Kaposiform hemangioendothelioma. International journal of clinical and experimental pathology, 2015. 8(10): p. 13711.

10. Ryu, Y.J., et al., Imaging findings of kaposiform hemangioendothelioma in children. European Journal of Radiology, 2017. 86: p. 198-205. [DOI:10.1016/j.ejrad.2016.11.015]

11. Azma, R., et al., Multifocal kaposiform hemangioendothelioma of soft tissue with bilateral pulmonary involvement in an adolescent. Korean journal of pediatrics, 2014. 57(11): p. 500. [DOI:10.3345/kjp.2014.57.11.500]

12. Ji, Y., et al., Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: a multicenter retrospective study. International Journal of Cancer, 2017. 141(4): p. 848-855. [DOI:10.1002/ijc.30775]

13. Cashell, J., et al., Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon in an infant: Successful treatment with prednisolone, vincristine, and addition of sirolimus. Pediatric Blood & Cancer, 2018. 65(12): p. e27305. [DOI:10.1002/pbc.27305]

14. Wang, H., et al., Sirolimus as initial therapy for kaposiform hemangioendothelioma and tufted angioma. Pediatric dermatology, 2018. 35(5): p. 635-638. [DOI:10.1111/pde.13600]

15. Koury, J., et al., Use of Sirolimus in a Premature Neonate With Kaposiform Hemangioedema. The Journal of Pediatric Pharmacology and Therapeutics, 2021. 26(2): p. 205-209. [DOI:10.5863/1551-6776-26.2.205]

Rights and permissions
	This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Designed & Developed by : Yektaweb