[Home ] [Archive]    
:: Home :: About Journal :: Registration :: Article Submission :: Contact us :: Site Map ::
:: Volume 2, Issue 4 (Summer 2010) ::
IJBC 2010, 2(4): 0-0 Back to browse issues page
Seroprevalence of Transfusion-transmitted Infections Among Multi-transfused Patients in Southwest Iran, Khuzestan Province
Abstract:   (8282 Views)
Background: Transfusion-transmi!ed infec"ons (TTIs) con"nue to be a problem in many parts of the world and mul"-transfused pa"ents are at a par"cularly increased risk for TTIs. The aim of this study was to determine the prevalence of Hepa""s C, Hepa""s B, and human immunodeficiency virus (HIV) infec"ons among mul"-transfused pa"ents in Khuzestan Province. Materials and Methods: A cross-sec"onal study was conducted on 349 mul"-transfusion pa"ents referred to the Hemoglobinopathy and Thalassemia Research Center from January 2007 to February 2008. Results: Out of 349 pa"ents, 205 (58.7%) and 144 (41.3%) were men and women, respec"vely. Mean ( ±SD) age of the par"cipants was 18.70±9.18 years. Of these 349 mul"-transfused pa"ents, 206 (59%) had thalassemia, 87 (24%) hemophilia, and 56 (16%) sickle cell anemia. The overall prevalence of HBsAg, an"-HCV, and an"-HIV were 0.6% (95% CI: 0-1.56), 28.4% (95% CI: 27.4-29.3), and 0.9% (95% CI: 0-1.86), respec"vely. The data indicate that an"-HCV posi"vity was significantly associated with an older age (P<0.001), longer dura"on of transfusion (P<0.001), and frequency of transfusion (P<0.001). Conclusion: Although it seems more sensi"ve screening tests and stringent donor selec"on procedures has reduced HCV infec"on, TTIs in mul"-transfusion pa"ents are s"ll a serious risk for these pa"ents. More stringent policy for blood product usage and con"nuous awareness programs for medical staff, general popula"on, and pa"ents are required to reduce the incidence of TTIs.
Keywords: Seroprevalence, Transfusion, Infec\"on, Iran
Full-Text [PDF 307 kb]   (3141 Downloads)    
: Research | Subject: Pediatric Hematology & Oncology
Received: 2012/01/10
Add your comments about this article
Your username or Email:

Write the security code in the box >


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Seroprevalence of Transfusion-transmitted Infections Among Multi-transfused Patients in Southwest Iran, Khuzestan Province. IJBC. 2010; 2 (4)
URL: http://ijbc.ir/article-1-284-en.html


Volume 2, Issue 4 (Summer 2010) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 3647