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IJBC 2016, 8(3): 86-87 Back to browse issues page
Lineage Switch in Childhood Leukemia: A Case Report and Review of Literature
Shiva Nazari, Fatemeh Malek *, Navid Zavvar
Abstract:   (2283 Views)

Acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. The conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. It has been rarely reported in the literature. In leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. Herein, we report a 7-year-old child with acute lymphoblastic leukemia which switched to acute myeloid leukemia upon relapse.

Keywords: Leukemia, Children, Cell lineage
Full-Text [PDF 387 kb]   (1346 Downloads)    
: case report | Subject: Pediatric Hematology & Oncology
Received: 2016/09/11 | Accepted: 2016/09/21 | Published: 2016/10/18
* Corresponding Author Address: Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
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Nazari S, Malek F, Zavvar N. Lineage Switch in Childhood Leukemia: A Case Report and Review of Literature. IJBC. 2016; 8 (3) :86-87
URL: http://ijbc.ir/article-1-688-en.html

Volume 8, Issue 3 (September 2016) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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