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:: Volume 10, Issue 1 (March 2018 2018) ::
IJBC 2018, 10(1): 28-30 Back to browse issues page
Extramedullary Hematopoiesis in a Patient with Transfusion Dependent Beta-Thalassemia Presenting with Cord Compression
Mehran Karimi * , Tahereh Zarei , Parisa Pishdad
Hematology Research Center, Shiraz University of Medical Sciences, Shiraz ,Iran
Abstract:   (351 Views)
Extramedullary hematopoiesis (EMH) is a physiological compensatory phenomenon occurring in many hemolytic anemias including thalassemia. Besides transfusion, radiotherapy, surgery or a combination of these modalities, hydroxyurea (HU) as an optimal treatment has been described occasionally. We described a case of beta-thalassemia major who has been on regular blood transfusion and developed EMH that was treated with HU combined with radiotherapy.
EMH should also be considered in thalassemia major patients, although it is more common in non-transfusion dependent thalassemia patients. HU combined with low dose radiotherapy along with regular blood transfusion are suggested as good treatment options for patients with EMH.
Keywords: Extramedullary hematopoiesis, Beta-thalassemia major, Hydroxyurea, Radiotherapy, Blood transfusion
Full-Text [PDF 1099 kb]   (356 Downloads)    
: case report | Subject: Adults Hematology & Oncology
Received: 2017/10/22 | Accepted: 2018/03/17 | Published: 2018/05/8
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Karimi M, Zarei T, Pishdad P. Extramedullary Hematopoiesis in a Patient with Transfusion Dependent Beta-Thalassemia Presenting with Cord Compression. IJBC. 2018; 10 (1) :28-30
URL: http://ijbc.ir/article-1-766-en.html


Volume 10, Issue 1 (March 2018 2018) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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