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In vitro Evaluation of the antibacterial activity of Platelet-rich Plasma against Selected Oral and Periodontal Pathogens
Shafagh Rostami , Mojgan Pourmokhtar *
Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran/Iran
Abstract:   (47 Views)
Background: Despite the availability of a wide range of antibiotics, bacterial infections are among important challenges for the healthcare system. Therefore, the introduction of new antimicrobial preparations such as platelet-rich plasma (PRP) could be suggested theoretically as a preventive measure for bacterial infections. We aimed to evaluate the in vitro antibacterial activity of PRP against three common oral bacteria.
Methods: In vitro antibacterial activity of PRP against Streptococcus Mitis, Streptococcus Mutans, and Neisseria Lactamica as three common oral/dental bacteria was determined by disc diffusion method. Baseline antibacterial activity was assessed by measuring the diameter zone of inhibition after 24 hours of incubation at 37 °C.
Results: PRP had strong in vitro antibacterial activity against Streptococcus Mitis, Streptococcus Mutans and Neisseria Lactamica with the mean zone of inhibition diameters of 6.73±0.52, 5.8±0.43 and 6.67±0.43 mm, respectively.
Conclusion: PRP is an effective antibacterial agent along with conventional antibiotic treatments against oral and periodontal infections.
Keywords: Platelet-rich plasma, Antibacterial activity, Oral and periodontal infections, Antibiotic treatment
Full-Text [PDF 648 kb]   (16 Downloads)    
: Research | Subject: Infectious Diseases
Received: 2018/02/28 | Accepted: 2018/04/21
* Corresponding Author Address: IBTO bldg., Hemmat Exp. Way, Next to the Milad Tower, Tehran, Iran P.O. Box: 14665-1157
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مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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