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Congenital Hypofibrinogenemia Detected during Preoperative Workup for Major Cardiac Surgery
K.B Chetak , Vilas Hiremath , K R Sujay , U S Dinesh Kumar , K Jagadish kumar *
Abstract:   (22 Views)
Afibrinogenemia or hypofibrinogenemia is a quantitative defect in fibrinogen. It is a rare disease with estimated frequency of 1 in 1,000,000 population. Routine preoperative screening tests of coagulation disorders are insufficient to detect subtle disorders of fibrinogen. Herein, we report a child who was supposed to undergo open cardiac surgery for a large atrial septal defect. Preoperative coagulation screening tests revealed minimal prolongation of prothrombin time which made us do further work-up. Finally, she was diagnosed with hypofibrinogenemia who was suggested to be congenital.
Keywords: Congenital hypofibrinogenemia, Afibrinogenemia, Cardiac surgery, Coagulation screening tests, Prolonged prothrombin time, Thrombin time
Full-Text [PDF 454 kb]   (8 Downloads)    
: case report | Subject: Pediatric Hematology & Oncology
Received: 2018/06/7 | Accepted: 2018/08/26
* Corresponding Author Address: Department of Pediatrics, Jss Medical College, Jss Academy of Higher Education and Research, Mysore, India
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مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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