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:: Volume 11, Issue 1 (March 2019 2019) ::
IJBC 2019, 11(1): 33-35 Back to browse issues page
BK Virus-Associated Hemorrhagic Cystitis in Children Suffering from Malignancies: Report of Three Cases
Shahla Ansari Damavandi, Neda Ashayeri *
Department of Hematology-Oncology, Ali Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, IR
Abstract:   (33 Views)
BK virus-associated hemorrhagic cystitis (HC) is frequent in patients undergoing bone marrow transplantation, but it rarely occurs among other immunosuppressed patients particularly in those who are receiving chemotherapy for hematologic malignancies. Herein, we report three children with malignancies suffering from hemorrhagic cystitis due to BK virus infection who were successfully improved.
Early detection of BK virus using RT-PCR technique was undertaken. With administration of antiviral agents; specifically, IVIG or leflunomide, BK virus-associated HC could be successfully managed in children affected by malignancies and consequently, chemotherapy of underlying disorder might be continued after virus elimination.
Keywords: BK virus, Cystitis hemorrhagic, Leflunomide, Immunosuppression
Full-Text [PDF 395 kb]   (9 Downloads)    
: case report | Subject: Pediatric Hematology & Oncology
Received: 2018/10/8 | Accepted: 2019/02/25
* Corresponding Author Address: Aliasghar hospital. Zafar street. Tehran. Iran
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Ansari Damavandi S, Ashayeri N. BK Virus-Associated Hemorrhagic Cystitis in Children Suffering from Malignancies: Report of Three Cases. IJBC. 2019; 11 (1) :33-35
URL: http://ijbc.ir/article-1-840-en.html


Volume 11, Issue 1 (March 2019 2019) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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