The Study of COVID-19 in an Iranian Family with Sickle Cell Disease

Rasouli Ghahfarokhi, Seyedeh Moloud; Dasmeh, Asghar; Farahmandi, Amir Yousef; Khedri, Azam; Asadi, Fatemeh; Piryaei, Fahimeh; Moradi, Leila

Volume 13, Issue 2 ( June 2021 2021) Iranian Journal of Blood and Cancer 2021, 13(2): 54-57 | Back to browse issues page

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Rasouli Ghahfarokhi S M, Dasmeh A, Farahmandi A Y, Khedri A, Asadi F, Piryaei F et al . The Study of COVID-19 in an Iranian Family with Sickle Cell Disease. Iranian Journal of Blood and Cancer 2021; 13 (2) :54-57
URL: http://ijbc.ir/article-1-1081-en.html

The Study of COVID-19 in an Iranian Family with Sickle Cell Disease

Seyedeh Moloud Rasouli Ghahfarokhi¹

, Asghar Dasmeh²

, Amir Yousef Farahmandi³

, Azam Khedri⁴

, Fatemeh Asadi⁵

, Fahimeh Piryaei ^*

⁶, Leila Moradi⁷

1- School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2- Unit of Health, Mahshahr petrochemical industries hospital, Bandar Mahshahr, Khuzestan, Iran
3- Department of English, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
4- Department of Clinical Biochemistry, Faculty of Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
5- Department of Molecular Genetics, Science and Research Branch, Islamic Azad University, Fars, Iran
6- Department of Molecular Medicine and Genetics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
7- Department of Epidemiology, School of Public Health, Hamadan University of Medical, Hamadan, Iran

Abstract: (2906 Views)

Coronavirus Disease 2019 (COVID-19) is a significant medical and public health problem in the world. It is believed that it can worsen in extreme conditions. Also, it is suggested that blood disorders such as sickle cell disease (SCD) may increase the risk of COVID-19 symptoms. The present study reports a family facing COVID-19, in which one of two members with SCD presented with fever, repeated cough and dizziness followed by acute chest syndrome leading to death. The remained members that had sickle cell trait manifested mild symptoms based on our findings. Although COVID-19 in individuals with SCD showed an increased risk for COVID19 compared with individuals with sickle cell trait, it seems that SCD cannot lead to worse condition in our patients.

Keywords: COVID-19, Sickle cell disease, Outcome

Full-Text [PDF 434 kb] (1089 Downloads)

: Case report | Subject: Infectious Diseases
Received: 2020/11/11 | Accepted: 2021/07/3 | Published: 2021/07/15

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