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:: دوره 10، شماره 3 - ( 6-1397 ) ::
جلد 10 شماره 3 صفحات 92-95 برگشت به فهرست نسخه ها
Adrenocortical Carcinoma Mimicking Pheochromocytoma: A case Report and Review of Literature
چکیده:   (127 مشاهده)
Adrenocortical carcinoma (ACC) is an uncommon malignancy originating from cortex of adrenal gland. The most common pitfall in diagnosis of ACC is to distinguish it from pheochromocytoma. Here we report a 62-year-old hypertensive man with presentation of dyspnea. The laboratory data showed an increase in urine cortisol and renin with a mild increase in aldosterone, but decrease in adrenocorticotropic hormone. Computerized tomography (CT) scanning revealed heterogeneous mass with enhancement in the adrenal region. The patient underwent surgery with an empirical diagnosis of pheochromocytoma, whereas ACC with high mitotic rate of about 50 mitoses/50 high-power field with vascular invasion was reported on histopathology. Immunohistochemistry was positive for Vimentin, Inhibin-α, Melan-A, and Synaptophysin. Ki-67 was positive in 25% of tumor cells. The results confirmed the diagnosis. ACC should be considered in differential diagnosis of adrenal masses especially in cases of hypertension and Cushing syndrome.
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: گزارش مورد | موضوع مقاله: Pathology
دریافت: ۱۳۹۷/۱/۲۵ | پذیرش: ۱۳۹۷/۷/۷ | انتشار: ۱۳۹۷/۸/۲
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Ramezani M, Azizi M, Sadeghi M. Adrenocortical Carcinoma Mimicking Pheochromocytoma: A case Report and Review of Literature. IJBC. 2018; 10 (3) :92-95
URL: http://ijbc.ir/article-1-798-fa.html

Adrenocortical Carcinoma Mimicking Pheochromocytoma: A case Report and Review of Literature. مجله خون و سرطان ايران. 1397; 10 (3) :92-95

URL: http://ijbc.ir/article-1-798-fa.html



دوره 10، شماره 3 - ( 6-1397 ) برگشت به فهرست نسخه ها
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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