[Home ] [Archive]    
:: Home :: About Journal :: Registration :: Article Submission :: Contact us :: Site Map ::
:: Volume 13, Issue 1 (March 2021 2021) ::
IJBC 2021, 13(1): 22-25 Back to browse issues page
Acute Lymphoblastic Leukemia Switch Lineage upon Relapse to Acute Bilineage Leukemia: A Case Report
Valiollah Mehrzad, Pardis Nematollahi *, Anahita Emami, Sayyideh Forough Hosseini
Pathology Department, OMID Professional Hospital, Isfahan University of Medical Science
Abstract:   (667 Views)
Although acute leukemia commonly relapses in adults, the conversion of leukemic cell lineage (lymphoid or myeloid) upon relapse has rarely taken place. “Lineage switch” is a term widely used to define the leukemic lineage transformation as assessed by morphology, cytochemistry, and immunophenotyping from diagnosis to relapse. In most lineage switch cases, B-cell lymphoblastic leukemia/lymphoma relapses as acute myeloid leukemia or vice versa. Here, we report an exceedingly rare case of T-cell acute lymphoblastic leukemia relapsing as mixed-phenotype acute leukemia.
Keywords: Acute lymphoblastic leukemia (ALL), Lineage switch, Mixed-phenotype acute leukemias (MPALs), Acute bilineage leukemia
Full-Text [PDF 2231 kb]   (246 Downloads)    
: case report | Subject: Adults Hematology & Oncology
Received: 2020/06/20 | Accepted: 2021/04/6 | Published: 2021/05/23
Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mehrzad V, Nematollahi P, Emami A, Hosseini S F. Acute Lymphoblastic Leukemia Switch Lineage upon Relapse to Acute Bilineage Leukemia: A Case Report. IJBC. 2021; 13 (1) :22-25
URL: http://ijbc.ir/article-1-1026-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 13, Issue 1 (March 2021 2021) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
Persian site map - English site map - Created in 0.04 seconds with 29 queries by YEKTAWEB 4331