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:: Volume 12, Issue 4 (December 2020 2020) ::
IJBC 2020, 12(4): 111-120 Back to browse issues page
Thrombotic Thrombocytopenic Purpura: Diagnosis and Treatment
Mohammadreza Saeidnia, Faride Nam Avar Jahromi, Elnaz Vaziee, Hossein Dehghani, Amir Mahmoodzade, Gholamhossein Tamaddon *
Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract:   (552 Views)
Thrombotic Thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathic disease, associated with thrombocytopenia and hemolytic anemia. It is caused by an enzymatic dysfunction responsible in cleavage of blood clotting factors. In this study we have tried to review the available approaches in diagnoses of the disease as well as treatment strategies. Based on the what the current review has provided, treatment policy depends on accurate diagnosis, it seems that developing a diagnostic and treatment guide for this disease is currently essential. Also, it’s necessary to study genetic types of TTP with more details because, hopefully, new techniques of gene therapy open a window to more stable treatments.
Keywords: Thrombotic thrombocytopenic purpura, Diagnosis, Gene therapy
Full-Text [PDF 533 kb]   (268 Downloads)    
: Review Article | Subject: Adults Hematology & Oncology
Received: 2020/05/27 | Accepted: 2020/10/7 | Published: 2020/12/31
* Corresponding Author Address: Shiraz University of Medical Sciences, Shiraz, Iran
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Saeidnia M, Nam Avar Jahromi F, Vaziee E, Dehghani H, Mahmoodzade A, Tamaddon G. Thrombotic Thrombocytopenic Purpura: Diagnosis and Treatment. IJBC. 2020; 12 (4) :111-120
URL: http://ijbc.ir/article-1-1011-en.html

Volume 12, Issue 4 (December 2020 2020) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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