Volume 16, Issue 2 (June 2024 2024)                   Iranian Journal of Blood and Cancer 2024, 16(2): 34-50 | Back to browse issues page

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Alotaibi S G, Alnouri M A, Sulaiman R M, Abduljaleel A, Bogari A F, Mufti H N. Optimizing Patient Blood Management in Cardiac Surgery: A Systematic Review. Iranian Journal of Blood and Cancer 2024; 16 (2) :34-50
URL: http://ijbc.ir/article-1-1535-en.html
Optimizing Patient Blood Management in Cardiac Surgery: A Systematic Review
Sultan Ghazzay Alotaibi * 1, Muneeb Ammar Alnouri2 , Rawaa Mahmoud Sulaiman3 , Abdulkhalek Abduljaleel4 , Ahmed Foad Bogari4 , Hani Nabeel Mufti5
1- Cardiac Center, King Fahd Armed Forces Hospital, Ministry of Defense, Jeddah, Saudi Arabia. , sultanalotaibi678@outlook.com
2- Cardiac Center, King Fahd Armed Forces Hospital, Ministry of Defense, Jeddah, Saudi Arabia.
3- Family Medicine Department, Dr. Sulaiman Fakeeh Hospital, Jeddah, Saudi Arabia
4- King Fahad General Hospital, Jeddah, Saudi Arabia.
5- King Faisal Cardiac Center, King Abdul-Aziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia
Abstract:   (394 Views)
Background: Heart diseases are typically treated with cardiac surgery, which often requires preoperative, intraoperative, and postoperative blood transfusion. However, blood transfusion is a risk factor for serious complications after cardiac surgery, including death. Patient Blood Management (PBM) programs were developed to mitigate the risks of blood transfusion by reducing its use in cardiac surgery.
Objective: This systematic review aims to study the currently published literature on PBM strategies that effectively reduce the rates of preoperative, intraoperative, and postoperative blood transfusion for cardiac surgery.
Methodology: This systematic review analyzed preoperative blood management strategies in cardiac surgery, focusing on studies published between 2018 and 2024 designed to reduce blood transfusion rates. The study utilized a modified 2022 protocol for systematic reviews and meta-analysis, grading evidence using a 2008 system, and selected 21 studies for a systematic review.
Results: The studies identified 12 PBM strategies, including iron therapy, Aminocaproic acid, Cardiopulmonary by-pass system, cell salvage, Perfusion Blood Collection, gel foam patches, Large-volume acute normovolemic hemodilution, Platelets Transfusion Therapy, Modified Ultrafiltration, TEM-based algorithms, and restrictive management of SVO2, which significantly reduced blood transfusion volumes and rates before, during, and after cardiac surgery.
Conclusion: The 12 PBM strategies identified are valuable additions to the current list, but further clinical evaluation is needed to improve their efficacy and safety in cardiac surgery.
Keywords: Blood transfusion, Cardiac surgery, Patient blood management, Systematic review, Bleeding disorder.
Full-Text [PDF 585 kb]   (171 Downloads)    
: Review Article | Subject: Adults Hematology & Oncology
Received: 2024/04/2 | Accepted: 2024/05/24 | Published: 2024/06/30
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