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Introducon: Acute hemorrhagic edema of infancy (AHEI) is a cutaneous leukocytoclas!c vasculi!s of infants, clinically characterized by acute development of peripheral edema and targetoid purpuric lesions on face and extremi!es. It is considered to be an uncommon form of cutaneous vasculi!s occurring in children younger than 2 years old. The clinical picture has a violent onset, a short benign course followed by spontaneous complete recovery. Case presenta!on: We describe two males with acute hemorrhagic edema. In one case the disease appeared a"er upper respiratory tract infec!on. Conclusion: AHEI is a benign disorder despite its drama!c appearance. The most striking classic features of the disease are the contrast between the acuteness of the cutaneous lesions and the good general condi!on of the pa!ent. Considering its clinical features, AHEI can be jus!fiably characterized as a unique disorder, dis!nct from Henoch–Schenlein Purpura (HSP).

Keywords: Acute hemorrhagic edema (this is not a MESH keyword), Infancy, Vasculi!s, Leukocytoclas!c

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