Volume 6, Issue 3 (Spring 2014)                   Iranian Journal of Blood and Cancer 2014, 6(3): 155-158 | Back to browse issues page

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Shamsian B S, Arabi N, Kazemi Aghdam M, Rouzrokh M, Ghojehvand N, Azma R, et al . Rosai-Dorfman Disease: A Case Report and Literature Review. Iranian Journal of Blood and Cancer 2014; 6 (3) :155-158
URL: http://ijbc.ir/article-1-461-en.html
Rosai-Dorfman Disease: A Case Report and Literature Review
Bibi Shahin Shamsian * , Nahid Arabi , Maryam Kazemi Aghdam , Mohsen Rouzrokh , Nozar Ghojehvand , Roksana Azma , Mohammad Kaji Yazdi , Samin Alavi , Mohammad Taghi Arzanian
Abstract:   (8423 Views)
Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms whose etiology remains poorly elucidated. The diagnosis is based on immunohistochemistry. Its treatment is poorly defined but the prognosis is usually favorable. Here we report a 14 year old boy who presented with massive bilateral cervical lymphadenopathy. Histopathological examination demonstrated lymphophagocytosis (emperipolesis) consistent with a diagnosis of Rosai-Dorfman disease. The clinical and histological aspects of the disease are discussed as a rare cause of lymphadenopathy. Key Words: Rosai-Dorfman disease, emperipolesis, case, Iran.
Keywords: Rosai-Dorfman disease, emperipolesis, case, Iran
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: Original Article | Subject: Pediatric Hematology & Oncology
Received: 2013/08/8 | Accepted: 2014/03/30 | Published: 2014/04/8
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