About the journal

The Iranian Journal of Blood and Cancer (IJBC) serves as the prestigious official scientific quarterly journal of the Iranian Pediatric Hematology and Oncology Society (IPHOS). IJBC which is indexed in Scopus, is accessible through online platforms, offering a remarkable compilation of scholarly manuscripts that delve into diverse dimensions of blood disorders and cancers. The journal warmly welcomes submissions of original papers, reviews, case reports, and letters to the Editor that revolve around the intricate realms of blood disorders and human malignancies. It is worth noting that the journal imposes no charges for manuscript submission, and authors are not subject to additional fees based on the length of their articles, inclusion of figures, or supplementary data.
View full Aims & Scope
Main Image

Iranian Journal of Blood and Cancer

2024، Volume 16، Number 1

Print ISSN: 2008-4595

Online ISSN: 2008-4609

Chairman: Mohammad Saeid Rahiminejad, MD

Editor-in-Chief: Hassan Abolghasemi, MD

Associate Editors: Davood Bashash, Ph.D ; Mohammad Faranoosh, MD

Review of endocrine complications in transfusion-dependent thalassemia

Major Beta thalassemia is a genetic disorder that often results in transfusion dependence and increased iron accumulation in the body. This iron overload can lead to tissue damage in various organs, including the heart, liver, and endocrine systems. Endocrine problems are a common complication in transfusion-dependent thalassemia, and addressing these issues can significantly improve patient's quality of life. The prevalence of endocrinopathy is high, particularly in patients with poor therapy compliance. The most common endocrine disorders include hypogonadism, growth disturbances, short stature, delayed puberty, acquired hypothyroidism and hypoparathyroidism, adrenal dysfunction, osteoporosis, diabetes, fertility issues, and complications during pregnancy. Early diagnosis and treatment of endocrine disorders can improve patients' quality of life and reduce social problems. Faranoush and colleagues conducted a thorough investigation of the various endocrine complications observed in individuals with thalassemia in the current review.The full-text of their article is available for download here.


From viral encounter to leukemic challenge: a case of isolated molecular relapse in a child with acute promyelocytic leukemia after SARS-CoV-2 infection
Abdolkarimi et al. presented a case study on a pediatric patient diagnosed with APL who suffered from a cerebral ischemic stroke. It is noteworthy that this stroke occurred following a SARS-CoV-2 infection, specifically during an isolated molecular relapse. The significance of this study is heightened due to the extensive research conducted on the neurological complications associated with COVID-19. Additionally, the authors elucidated the mechanism through which SARS-CoV-2 can invade the nervous system and potentially induce neurological harm. The full-text of their article is available for download here.

Genetics and pathophysiology of severe congenital neutropenias (SCNs)
Younesian et al. conducted a comprehensive review of current research examining the biological role of genes associated with the SCN and the effects of genetic mutations on the pathogenesis of neutropenia. Their primary objective was to elucidate the underlying mechanisms that contribute to the development of SCN-related disorders, with a particular emphasis on mutations in SCN1 to SCN9 and X-linked SCN (XSCN). The authors' detailed analysis sheds light on the complex interplay between genetic factors and disease pathophysiology.
The full-text of their article is available for download here, providing a valuable resource for further investigation into this important area of medical research.


Recent research indicates that microbes may have a significant impact on the development of cancer. The interaction between microbes and the host's immune system, known as the immuno-oncology-microbiome (IOM) axis, is a common theme in microbial involvement in cancer. Scientists are exploring different approaches to manipulate the gut or tumor microbiome as potential treatments for cancer. Studies suggest that the gut microbiome can affect the effectiveness of cancer immunotherapy, and it may be possible to engineer certain bacteria to target cancerous growths. Future research in this field will likely focus on further investigating the IOM axis and developing targeted therapies that manipulate the microbiome to improve cancer outcomes.
The Iranian Journal of Blood and Cancer (IJBC) has organized a special issue to gather original research and review articles that explore the latest advancements and emerging trends regarding the role of the microbiome in cancer. By presenting the most significant contributions in this area, this issue aims to deepen our understanding of how the microbiome can trigger cancer and how these small microorganisms can impact the treatment of different types of cancer.

              SUBMISSION DEADLINE: 1 April 2024

Journal Information

  • Journal Title:                                               Iranian Journal of Blood and Cancer
  • Publisher:                                                                            Iranian Pediatric Hematology & Oncology Society
  • Print ISSN:                                                                   2008-4595
  • Online ISSN:                                                                    2008-4609
  • Release interval:                                                              Quarterly
  • Journal language:                                                             English
  • Chairman:                                                                           Dr. Mohammad Saeid Rahiminejad
  • Editor-in-Chief:                                                              Dr. Hassan Abolghasemi
  • Associate Editors:                                                             Dr.Davood Bashash; Dr. Mohammad Faranoosh
  • Executive Editor:                                                          Amir-Mohammad Yousefi
  • Current Issue: 2024، Volume 16، Number 1

Newsletter subscription

Enter your email address to have site news and announcements delivered directly to your inbox.


Copyright Policy

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

© 2024 All Rights Reserved | Iranian Journal of Blood and Cancer

Designed & Developed by : Yektaweb