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:: Volume 14, Issue 3 (September-2022 2022) ::
IJBC 2022, 14(3): 32-40 Back to browse issues page
Overview on Evans syndrome: In the course of Covid-19 pandemic; essentials and approaches
Gholamhossein Tamaddon *, Pooria Fazeli, Mohammadreza Saeidnia, Arghavan Farzi, Navid Pooresmaeil, Mohammad hamed Javanmardi
Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. tamaddon.g@gmail.com
Abstract:   (40 Views)
Redundant studies proved coronavirus infection results from a defect in a suitable immune response that may exacerbate immune-inflammatory reactions like cytokine storm and autoimmunity. Evans syndrome (ES) is a rare chronic autoimmune disease that distinguishes it from autoimmune hemolytic anemia (AIHA) and immune thrombocytopenic purpura (ITP). Reports have shown significant differences in immune cells and laboratory parameters in Evans syndrome/COVID-19 co-infected patients. Also, the contribution between autoimmune diseases and SARS-CoV-2 infection could result in immune response disequilibrium that considers a possible mechanism for ES development. Moreover, we will briefly explain the double-edged sword role of immunosuppressive drugs in Evans syndrome/COVID-19 co-infected patients. Generally, the pathophysiology of SARS-CoV-2 in hematologic autoimmune disorders progression, particularly ES, remains unclear, but some investigations explain the COVID-19 infection mechanism in the mentioned disorders development. The purpose of the current study is to look at the coronavirus effects on Evans syndrome aggravation, the immune cells and laboratory markers alterations in Evans syndrome/COVID-19 co-infected patients, the coronavirus effects on Evans syndrome patients during their pregnancy, and the Evans syndrome / COVID-19 co-infected patient management.
Keywords: Coronavirus, COVID-19, Evans syndrome, Autoimmune disease, SARS-CoV-2
Full-Text [PDF 641 kb]   (48 Downloads)    
: Review Article | Subject: Immunology
Received: 2022/01/12 | Accepted: 2022/08/16 | Published: 2022/09/19
* Corresponding Author Address: Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. tamaddon.g@gmail.com
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Tamaddon G, Fazeli P, saeidnia M, Farzi A, Pooresmaeil N, Javanmardi M H. Overview on Evans syndrome: In the course of Covid-19 pandemic; essentials and approaches. IJBC 2022; 14 (3) :32-40
URL: http://ijbc.ir/article-1-1216-en.html


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Volume 14, Issue 3 (September-2022 2022) Back to browse issues page
مجله ی خون و سرطان ایران Iranian Journal of Blood and Cancer
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